MoleMap South Melbourne is a skin cancer screening clinic operating as an accredited MoleMap partner within the Clarendon Centre at 261 Clarendon Street. The clinic is entered from the Dorcas Street side of the centre, on the ground floor near Oporto and St Lukes Anglican Church. The clinic specialises in mole mapping and skin cancer detection, using MoleMap's imaging technology to capture and track skin lesions over time. Services include Full Body MoleMap, SkinCheck, SkinCheck+ and skin cancer treatment referrals. Images and results are reviewed by qualified dermatologists as part of the diagnostic process, and staff have completed MoleMap accredited training. Appointments are required and can be booked online through the MoleMap website, or by phone through the national booking line. The clinic operates Monday to Friday during business hours, with Saturday appointments available on a fortnightly basis. Afterpay is accepted for eligible treatments, and fees vary depending on the service booked. The Dorcas Street entrance is wheelchair accessible, and visitors can access the Clarendon Centre car park nearby, with free parking offered for a limited period. The clinic's location within a busy shopping precinct makes it a practical option for South Melbourne locals and visitors wanting a skin check alongside other errands.